Fax: +49 (0) 761 892535
is now a devision of ORSAtec

Come and meet us!

On the 15th and 16th of June at Histologica 2018 in Oberhausen, exhibition stand No. 22. Or you take part in our workshop “Covering free of xylene with EUKITT© UV”: Friday from 10.00 am or Saturday from 1 pm.

We're looking forward to see you!

Adhesion slides for microscopy

Adhesion slides

In most cases paraffin sections stick to the slides without aids and are not detached from the slide during the staining process.
Modern techniques such as immunohistology or antibody staining are carried out under extreme conditions, which can detach the paraffin sections from the slide. (e.g. treatment with highly alkaline solutions (> pH 8))

Especially for very valuable sample material, or the use of very expensive tests, are such losses a major problem.

So-called adhesives avoid such detachments. These adhesives are applicated by coated slides.

Classic alternatives are self-made coatings (glycoproteins such as protein glycerol (albumine) or gelatine). Alternatively commercially available adhesive slides are used. [1] The high sample throughput and the time pressure in modern economy lead to more and more rationalization, so the self-coating is no longer state of the art.

Modern biological methods for the detection of nucleic acids (RNA or DNA) in tissues, individual cells or metaphase chromosomes [2] or in-situ PCR [3] and microarray [4] require specific adherent slide surfaces. The procedures expose the tissue sections to elevated temperatures and repeated washes. Therefore the bonding of tissue to the glass surface is reduced.

The adhesives have to be free of autofluorescence or disturbing background effects.


We will gladly make you an offer!

Do you have any question to our products or are you interested in additional information? We are looking forward to hear from you.

(1) Histotechnik: Praxislehrbuch für die Biomedizinische Analytik, 2. Auflage, Gudrun Lang, Springer Verlag, Wien 2012.
(2) https://de.wikipedia.org/wiki/In-situ-Hybridisierung
(3) http://www.spektrum.de/lexikon/biologie/in-situ-pcr/34225
(4) https://de.wikipedia.org/wiki/Microarray